
Smith calls his 31 years in extension
the best years of his life. His
career, combined with judicious investments,
also provided him with
enough savings that he can make
charitable donations—a development
that caught him by surprise.
“When I look back, I really am
amazed at my net worth and how I did it,” Smith says. “When I took
my job with extension, I started to
make a few more dollars. I wasn’t
married so I started to put every
nickel I earned into buying stocks
and CDs. I was fortunate because
dollars multiplied much faster than
I thought. Not sure I can explain
it except to say that my wife and
I made good investments, we both
were thrifty, and it just kind of materialized.
Now I have money to
give, and Penn State always was my
first choice.”
Smith Professor Gary Perdew
is a respected scholar conducting
research into how chemicals in the environment can affect human
health. He is recognized internationally
for his studies on the
function and molecular dynamics
of the cellular receptor for aromatic
hydrocarbons (Ah). His research
is aimed at determining how environmental
pollutants, especially dioxins,
react with the Ah receptor to
cause alterations in gene expression
and lead to diseases such as cancer.
Perdew says Smith’s generosity
has provided vital support for his
work. “The Smith Professorship
has allowed me to start a high-impact,
long-term project that would
be otherwise difficult to get funding
for without having first developed
a transgenic mouse that exexpresses
the human Ah receptor,”
he says. The funds enabled him to
hire Jennifer Schroeder, a postdoctoral
fellow who helped to develop
a mouse line that expresses the
human form of the Ah receptor,
which responds to much of the environmental
exposure to dioxin or
polycyclic aromatic hydrocarbon
(e.g., from smoking or burning of
fossil fuels).
“She is an excellent scientist,”
he says. “Now that a transgenic
mouse has been developed,
we can seek outside funding for
an expanded project using it. The
human form of this receptor appears appears
to be quite different from
the mouse form, so this modified
mouse will be important for understanding
the risks of dioxin exposure
in humans. This project
would not be possible without support
from this professorship.”
For his part, Smith is just glad
that he’s in a position to give back
in a way that’s making a real difference.
“It’s been a pleasure to be
able to give money to some charitable
things that are important,” he
says. “We have no children, and life
has been very generous to me. So,
showing my appreciation through
education at Penn State is the best
thing I can do to help.”
—Gary Abdullah
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