
Kapur is internationally recognized for his pioneering work
in completely sequencing the genomes of several of the world’s
major human and animal pathogens, including Pasteurella,
Mycobacterium, Staphylococcus, Brucella, Lawsonia, and
Cryptosporidium. The results of these studies have provided key
insights into how microbes cause disease and have led to the
development of powerful new diagnostic tests and novel vaccines
with major global implications in disease control.
A holder of six U.S. patents, Kapur also leads an international
consortium of scientists studying Johne’s disease, a chronic
inflammatory intestinal disease of ruminants such as cattle, goats,
deer, and antelope. Johne’s disease affects about 22 percent of
dairy herds in the United States and causes substantial economic
losses to farmers worldwide. The bacteria that causes Johne’s
disease also has been associated with Crohn’s disease in
humans and may represent a potential food-safety concern.
“Our collaborative work on Johne’s disease
has led to improvements in diagnostic tests, a better understanding
of mechanisms of disease transmission and pathogenesis, and the
identification of new vaccine candidates,” Kapur explains.
“Our consortium also has enabled the development of online
training programs on Johne’s disease for veterinarians and
producers.”
What drew Kapur to Penn State? “The greatest
strengths of the Department of Veterinary and Biomedical Sciences
are the extraordinarily high caliber and productivity of the faculty,
the incredible diversity of programmatic interests, and the direct
linkage to the real world through Penn State’s Animal Diagnostic
Laboratory and the cooperative-extension program,” says Kapur,
who earned his doctorate in veterinary science from Penn State in
1991—in the same department that he now has returned to lead.
As the university continues to invest in new infectious disease
laboratory facilities and faculty, Kapur believes the future is
bright—for teaching as well as research. “This is an
extremely important area that impacts human, animal, and plant health,”
Kapur points out. “Our new and successful undergraduate major
in Immunology and Infectious Disease is a testament to our strong
commitment not only to infectious-disease research, but also to
our desire to leverage our excellence in this area to enhance undergraduate
training opportunities at Penn State".
—Chuck Gill
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